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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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 Posted: Mon Dec 31, 2012 6:29 am Post subject: CPU Project of the Month January 2013=> Fight Malaria |
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In another extremely close vote, nearly a quadra-tie, FightMalaria@Home is our CPU PotM for January. This is a very interesting project because it works with compounds that have already shown promise against this disease.
| Quote: | The Plasmodium falciparum genome has been sequenced, the proteome has been mapped, and protein expression has been confirmed at various stages in this apicoplexan's life cycle. Numerous crystal structures of target proteins are also available, and the remainder have been modelled using available structural templates. Excitingly, large research organisations (GSK, Novartis) have already tested millions of compounds and found nearly 19,000 hits that show promising activity against Plasmodium falciparum [MMV]. But they don't know which target protein is inhibited by these compounds. Drug discovery and development will be significantly enhanced by knowing the target protein for each of these hits.
Problem: We plan to dock each of the 18,924 hits into structures of each of the 5,363 proteins in the malaria parasite. The computational power needed is enormous.
http://www.fight-malaria.org/
Url to join:
http://boinc.ucd.ie/fmah/ |
Tasks ready to send 54,967
Starting stats:
8th Place
1,857,978 Total points
11,919 daily average production over past week
8th place Formula Boinc |
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Mon Dec 31, 2012 11:56 pm Post subject: |
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It is time to skill some mosquitoes. Take your bug spray and start spraying.
Ni
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Wed Jan 02, 2013 9:23 am Post subject: |
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Forgot how much this project hogs my BOINC over all other projects. At least it is just for the month.
Ni
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sat Jan 05, 2013 7:41 am Post subject: |
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Keep swatting 'em, we're about to be steam-rollered by Seti.USA...
Dow is in The Top 10 on this project. 
'Stones:
The Knights Who Say Ni! passed 1,900,000
Wabbit98 20,000
GWH0744 10,000
Idan passes 10,000
Christopher Bogusch passed 5,000
Sir Stooper 5,000
Plomos passed 2,000
Colleen 500 |
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Tue Jan 08, 2013 6:24 pm Post subject: |
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| Killerrabbit wrote: | | Forgot how much this project hogs my BOINC over all other projects. At least it is just for the month. Ni |
Yeah wazzup widdat? I had to stop running Fightmalaria a month or so ago because the client couldn't suspend it, I had to Klonk it. Now it behaves better - it suspends, but won't let other projects get work?
Anyway - the Simap Scrambler is over - time to get back to zapping!
Milestones:
The Knights Who Say Ni! 2,000,000
DoW 1,200,000
Gemjunkie[TeaM] 250,000
Yankton 50,000
Sir Stooper 10,000
Christopher Bogusch 6,000
Adam Alexander 5,000 |
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Gemjunkie
Prince
Joined: 03 Jul 2010
Posts: 3519
Location: Earth, lately
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| Posted: Wed Jan 09, 2013 1:39 pm Post subject: |
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I started running into a bunch of computation errors accross different shrubbers. 
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Gemjunkie
Prince
Joined: 03 Jul 2010
Posts: 3519
Location: Earth, lately
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| Posted: Wed Jan 09, 2013 3:22 pm Post subject: |
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Bunch of errors triggers a 24hr. project backoff so I'm adding secondary projects. 
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stooper101
Prince
Joined: 16 May 2009
Posts: 1248
Location: Cheese Country
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| Posted: Wed Jan 09, 2013 8:37 pm Post subject: |
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Had the same problem here. Came back from work with a huge list of errors. I forced an update and most everything is computing fine now. Looks like the project was running through a bad batch. They have a news item about it.
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Wed Jan 16, 2013 6:07 am Post subject: |
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Production has doubled to almost 24K daily average over the past week.
Tasks ready to send 35,502
Skeeter Swats:
Yankton passes 70,000
Logan 60,000
Sir Stooper passed 40,000
Sir Mifun Fat in a Right Place 40,000
Idan passes 30,000
Wabbit98 25,000
LanDroid 20,000
Ali_Vakilzadeh 8,000
Christopher Bogusch 7,000
Catweazel 5,000
Plomos 5,000
Colleen 2,000 |
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Joe Bloggs
Squire
Joined: 12 Jan 2013
Posts: 19
Location: Hong Kong
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| Posted: Wed Jan 16, 2013 12:24 pm Post subject: |
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Bit late to the party, but I just joined the project and will start shrubbing with my 6-barrel Phenom as soon as the existing cache of WUs work their way out... which may be awhile 
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Thu Jan 24, 2013 6:00 pm Post subject: |
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KWSN production is up to almost 32K daily average.
Stones:
The Knights Who Say Ni! passes 2,500,000
Sir Mifun Fat in a Right Place passed 70,000
Idan passes 50,000
LanDroid passed 30,000
Murdog passes 20,000
Joe Bloggs passes 20,000
Colleen passes 3,000
Agostino Galegati passes 3,000 |
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