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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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 Posted: Sun Nov 11, 2012 9:32 am Post subject: |
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WCG / GO Fight Malaria Science
| Quote: | We are performing this project on World Community Grid in order to discover promising candidate compounds that can be developed into new drugs that cure drug-resistant strains of malaria. In this project we will computationally evaluate millions of chemical compounds against different molecular drug targets from the malaria parasite. These computations will estimate the ability of the chemical compounds to disable the particular proteins that the Plasmodium parasite needs to survive, multiply, and infect humans. That is, these "docking calculations" predict whether a particular compound can bind to and disable key components of the molecular machinery that the malaria parasite needs to survive and reproduce. Data from these GO Fight Against Malaria experiments (and data from all World Community Grid projects) are available to the public.
...Because of the power of World Community Grid, what we can accomplish with one year of the GO Fight Against Malaria project could take us well over one hundred years to achieve, using the resources we normally have available.
http://gofightagainstmalaria.scripps.edu/ |
http://www.worldcommunitygrid.org/research/gfam/overview.do |
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Concrete-mixing Moose
Prince
Joined: 30 Apr 2012
Posts: 567
Location: The Joyce Grenfell Home for the Distressed
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| Posted: Sun Nov 11, 2012 10:33 am Post subject: |
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| LanDroid wrote: | Fight Malaria
Any update on the aggressive behavior of these WU's, are they behaving better on the Boinc playground?
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Nothing yet. Still misbehavin'.
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branjo
Prince
Joined: 05 Jan 2006
Posts: 746
Location: Slovakia
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| Posted: Sun Nov 11, 2012 4:32 pm Post subject: |
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| LanDroid wrote: | WCG / GO Fight Malaria Science
| Quote: | We are performing this project on World Community Grid in order to discover promising candidate compounds that can be developed into new drugs that cure drug-resistant strains of malaria. In this project we will computationally evaluate millions of chemical compounds against different molecular drug targets from the malaria parasite. These computations will estimate the ability of the chemical compounds to disable the particular proteins that the Plasmodium parasite needs to survive, multiply, and infect humans. That is, these "docking calculations" predict whether a particular compound can bind to and disable key components of the molecular machinery that the malaria parasite needs to survive and reproduce. Data from these GO Fight Against Malaria experiments (and data from all World Community Grid projects) are available to the public.
...Because of the power of World Community Grid, what we can accomplish with one year of the GO Fight Against Malaria project could take us well over one hundred years to achieve, using the resources we normally have available.
http://gofightagainstmalaria.scripps.edu/ |
http://www.worldcommunitygrid.org/research/gfam/overview.do |
Despite all of this, we are still ranked 127th in WCG. And falling down. NI!
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Sun Nov 11, 2012 11:31 pm Post subject: |
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I am not having trouble with FightingMalaria@Home, they have work by the bucketful.
Ni
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Concrete-mixing Moose
Prince
Joined: 30 Apr 2012
Posts: 567
Location: The Joyce Grenfell Home for the Distressed
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| Posted: Mon Nov 12, 2012 2:25 pm Post subject: |
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| Killerrabbit wrote: | I am not having trouble with FightingMalaria@Home, they have work by the bucketful.
Ni |
Not any more they don't!
| Quote: | Hi Guys,
There will be a short downtime today due to a hardware fault. All currently running tasks will be completed but new tasks will not be issued. I hope to have everything running again in the next few hours.
Thanks for you patience,
Kevin |
Computing status -
Tasks ready to send 0
Tasks in progress 91,855
UPDATE (and this does n't bode well)
| Quote: | Unfortunately it's going to take a little longer than expected. We will be back up and running in 24 hours.
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Sir Papa Smurph
Cries like a little girl
Joined: 18 Jul 2006
Posts: 4430
Location: Michigan
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| Posted: Mon Nov 12, 2012 6:28 pm Post subject: |
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Yeah, I've heard that before
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and a Really Hoopy Frood who always knows where his Towel is...
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Tue Nov 13, 2012 7:16 pm Post subject: |
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For the CPDN said it would be a short time and they are still down.
Ni
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Concrete-mixing Moose
Prince
Joined: 30 Apr 2012
Posts: 567
Location: The Joyce Grenfell Home for the Distressed
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| Posted: Wed Nov 14, 2012 4:23 pm Post subject: |
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FightMalaria@home is up again - I've got some work and this was posted on the messageboard
| Quote: | We're back online now. We're now using an extra server for the results database which should improve the performance of the main server.
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Mifun
Duke
Joined: 08 Jan 2012
Posts: 265
Location: Russia
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| Posted: Thu Nov 15, 2012 3:32 pm Post subject: |
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Got my first badge
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Thu Nov 15, 2012 6:48 pm Post subject: |
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She's a beaut!
Fight Malaria
Moved up 2 places to 8th! Production up to 61K daily.
Milestones:
DoW passes 650,000
Gemjunkie[TeaM] 100,000
Logan 30,000
Sir Mifun Fat in a Right Place 20,000
alienware 20,000
Sir Papa Smurph 10,000
Emmy&Oreo 10,000
LanDroid 10,000
Malaria Control
Production has doubled to 45K daily.
Milestones:
efs300 1,800,000
Giles Tanner 600,000
Robert passed 350,000
Semicolon 250,000
LanDroid 60,000
Sir Stooper 50,000
dusc 40,000
Wabbit98 20,000
Sir Papa Smurph 10,000
WCG / GO Fight Malaria
Production is way up to 171K daily.
Milestones:
Idan Shifres 1,300,000
branjo 1,000,000
Kemanmaldea 750,000
ATaRi 450,000
Sir Mifun 50,000
Murdog8 40,000
flommi 30,000
Sir Dancealot 25,000
Tericon passes 10,000
dhm1982 10,000 |
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branjo
Prince
Joined: 05 Jan 2006
Posts: 746
Location: Slovakia
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| Posted: Fri Nov 16, 2012 1:22 pm Post subject: |
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| Mifun wrote: | Got my first badge
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Pozdravlenia Mifun. Ubivaj moskity
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Fri Nov 16, 2012 4:58 pm Post subject: |
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You can't these badges as police badges.
Ni
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Concrete-mixing Moose
Prince
Joined: 30 Apr 2012
Posts: 567
Location: The Joyce Grenfell Home for the Distressed
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| Posted: Fri Nov 16, 2012 6:20 pm Post subject: |
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| Killerrabbit wrote: | You can't these badges as police badges.
Ni |
Are you taking posting lessons from Grizz? 
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Gemjunkie
Prince
Joined: 03 Jul 2010
Posts: 3519
Location: Earth, lately
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| Posted: Fri Nov 16, 2012 8:17 pm Post subject: |
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(older, before split CPID)
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branjo
Prince
Joined: 05 Jan 2006
Posts: 746
Location: Slovakia
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| Posted: Sat Nov 17, 2012 4:49 am Post subject: |
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| Quote: | We've discovered some promising candidates against enoyl-acyl-carrier-protein reductase
Hi Everybody,
In addition to celebrating the GO Fight Against Malaria project's first birthday today, I have some other good news to share with all of you. In the results of Exp. 5, we've discovered some promising new inhibitors of ENR (enoyl-acyl-carrier-protein reductase). This is an example of targeting malaria side-ways, instead of head on... |
https://secure.worldcommunitygrid.org/forums/wcg/viewthread_thread,34265
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Mifun
Duke
Joined: 08 Jan 2012
Posts: 265
Location: Russia
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| Posted: Sat Nov 17, 2012 11:58 am Post subject: |
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| Killerrabbit wrote: | You can't these badges as police badges.
Ni |
I'm Lord of Sealand, yes i can.
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sun Nov 25, 2012 1:48 pm Post subject: |
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Fight Malaria 'Stones:
The Knights Who Say Ni! passed 1,400,000
DoW 850,000
Gemjunkie[TeaM] 150,000
Yankton 30,000
alienware 30,000
Sir Papa Smurph 25,000
Wabbit98 10,000
Murdog 9,000
Malaria Control 'Stones:
We moved up one place to 12th.
Tony 1,000,000
DannyBoy 250,000
dusc passed 100,000
Wabbit98 25,000
dhernandez 10,000
Bellator 9,000
WCG 'Stones:
A Shrubbery 13,000,000
Juha Seppinen passes 1,600,000
Liquidware 1,600,000
Blurf 1,400,000
dtruchan 1,400,000
branjo passed 1,300,000
Kemanmaldea 800,000
ac_dc 550,000
scott 550,000
Sir Mifun 60,000
dhm1982 passes 30,000
Tericon passes 30,000
Elunes32792 25,000
konwron 10,000 |
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sat Dec 01, 2012 8:13 pm Post subject: |
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Final Stats:
Malaria Control
12th Place +1
23,391,134 points +773,892
24K average daily points
10th place Formula Boinc -1
Fight Malaria
7th Place +5
1,714,876 points +1,116,370
RAC 3rd place +7
7th Place Formula Boinc +5
WCG / GO Fight Malaria
126th Place +/- 0
57,898,904 Points +3,047,339
113K daily average production in final week
Thanks for participating in the KWSN skeeter smack down! |
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Sat Dec 01, 2012 11:58 pm Post subject: |
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Many mosquitoes died for this shrubbing.
Ni
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