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CPU Project of the Month January 2013=> Fight Malaria

 
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LanDroid
Prince
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Joined: 11 Jun 2002
Posts: 4466
Location: Cincinnati, OH U.S.

PostPosted: Mon Dec 31, 2012 6:29 am    Post subject: CPU Project of the Month January 2013=> Fight Malaria Reply with quote

In another extremely close vote, nearly a quadra-tie, FightMalaria@Home is our CPU PotM for January. This is a very interesting project because it works with compounds that have already shown promise against this disease.

Quote:
The Plasmodium falciparum genome has been sequenced, the proteome has been mapped, and protein expression has been confirmed at various stages in this apicoplexan's life cycle. Numerous crystal structures of target proteins are also available, and the remainder have been modelled using available structural templates. Excitingly, large research organisations (GSK, Novartis) have already tested millions of compounds and found nearly 19,000 hits that show promising activity against Plasmodium falciparum [MMV]. But they don't know which target protein is inhibited by these compounds. Drug discovery and development will be significantly enhanced by knowing the target protein for each of these hits.

Problem: We plan to dock each of the 18,924 hits into structures of each of the 5,363 proteins in the malaria parasite. The computational power needed is enormous.

http://www.fight-malaria.org/

Url to join:
http://boinc.ucd.ie/fmah/

Tasks ready to send 54,967

Starting stats:
8th Place
1,857,978 Total points
11,919 daily average production over past week
8th place Formula Boinc
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Killerrabbit
Major Oblivion
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Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!

PostPosted: Mon Dec 31, 2012 11:56 pm    Post subject: Reply with quote

It is time to skill some mosquitoes. Take your bug spray and start spraying.

Ni
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Killerrabbit
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PostPosted: Wed Jan 02, 2013 9:23 am    Post subject: Reply with quote

Forgot how much this project hogs my BOINC over all other projects. At least it is just for the month.

Ni
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LanDroid
Prince
Prince


Joined: 11 Jun 2002
Posts: 4466
Location: Cincinnati, OH U.S.

PostPosted: Fri Jan 04, 2013 7:30 pm    Post subject: Reply with quote

A fightmalaria charity team? Not sure what the purpose is, perhaps Sir Searcher can explain...

http://www.kwsnforum.com/viewtopic.php?t=17940&sid=23f39dab05af6d273fda231a6e37188b
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LanDroid
Prince
Prince


Joined: 11 Jun 2002
Posts: 4466
Location: Cincinnati, OH U.S.

PostPosted: Sat Jan 05, 2013 7:41 am    Post subject: Reply with quote

Keep swatting 'em, we're about to be steam-rollered by Seti.USA...

Dow is in The Top 10 on this project. Shocked

'Stones:
The Knights Who Say Ni! passed 1,900,000

Wabbit98 20,000
GWH0744 10,000
Idan passes 10,000
Christopher Bogusch passed 5,000
Sir Stooper 5,000
Plomos passed 2,000
Colleen 500
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LanDroid
Prince
Prince


Joined: 11 Jun 2002
Posts: 4466
Location: Cincinnati, OH U.S.

PostPosted: Tue Jan 08, 2013 6:24 pm    Post subject: Reply with quote

Killerrabbit wrote:
Forgot how much this project hogs my BOINC over all other projects. At least it is just for the month. Ni

Yeah wazzup widdat? I had to stop running Fightmalaria a month or so ago because the client couldn't suspend it, I had to Klonk it. Now it behaves better - it suspends, but won't let other projects get work?

Anyway - the Simap Scrambler is over - time to get back to zapping!


Milestones:
The Knights Who Say Ni! 2,000,000

DoW 1,200,000
Gemjunkie[TeaM] 250,000
Yankton 50,000
Sir Stooper 10,000
Christopher Bogusch 6,000
Adam Alexander 5,000
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Gemjunkie
Prince
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Joined: 03 Jul 2010
Posts: 3519
Location: Earth, lately

PostPosted: Wed Jan 09, 2013 1:39 pm    Post subject: Reply with quote

I started running into a bunch of computation errors accross different shrubbers. #Mad
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Gemjunkie
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Joined: 03 Jul 2010
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PostPosted: Wed Jan 09, 2013 3:22 pm    Post subject: Reply with quote

Bunch of errors triggers a 24hr. project backoff so I'm adding secondary projects. Rolling Eyes
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stooper101
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Joined: 16 May 2009
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Location: Cheese Country

PostPosted: Wed Jan 09, 2013 8:37 pm    Post subject: Reply with quote

Had the same problem here. Came back from work with a huge list of errors. I forced an update and most everything is computing fine now. Looks like the project was running through a bad batch. They have a news item about it.
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LanDroid
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Joined: 11 Jun 2002
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Location: Cincinnati, OH U.S.

PostPosted: Wed Jan 16, 2013 6:07 am    Post subject: Reply with quote

Production has doubled to almost 24K daily average over the past week.
Tasks ready to send 35,502

Skeeter Swats:
Yankton passes 70,000
Logan 60,000
Sir Stooper passed 40,000
Sir Mifun Fat in a Right Place 40,000
Idan passes 30,000
Wabbit98 25,000
LanDroid 20,000
Ali_Vakilzadeh 8,000
Christopher Bogusch 7,000
Catweazel 5,000
Plomos 5,000
Colleen 2,000
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Joe Bloggs
Squire
Squire


Joined: 12 Jan 2013
Posts: 19
Location: Hong Kong

PostPosted: Wed Jan 16, 2013 12:24 pm    Post subject: Reply with quote

Bit late to the party, but I just joined the project and will start shrubbing with my 6-barrel Phenom as soon as the existing cache of WUs work their way out... which may be awhile Embarassed
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LanDroid
Prince
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Joined: 11 Jun 2002
Posts: 4466
Location: Cincinnati, OH U.S.

PostPosted: Thu Jan 24, 2013 6:00 pm    Post subject: Reply with quote

KWSN production is up to almost 32K daily average.

Stones:
The Knights Who Say Ni! passes 2,500,000

Sir Mifun Fat in a Right Place passed 70,000
Idan passes 50,000
LanDroid passed 30,000
Murdog passes 20,000
Joe Bloggs passes 20,000
Colleen passes 3,000
Agostino Galegati passes 3,000
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