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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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 Posted: Wed Oct 31, 2012 6:27 pm Post subject: |
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Malaria Control
Starting stats:
13th place
22,617,242 total points
21.4K average daily points in last week
23,744 RAC 8th place
9th place Formula Boinc
Fight Malaria
12th place
598,506 total points
8,305 average daily points in last week
8,255 RAC 10th place
12th place Formula Boinc
WCG / GO Fight against Malaria
Ummm haven't figgered out the stats on this sub-project?  But you can score badges!
Oh well, here are overall WCG stats:
126th place
54,851,565 total points
51.5K average daily points in last week
60,362 123rd place |
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branjo
Prince
Joined: 05 Jan 2006
Posts: 746
Location: Slovakia
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| Posted: Thu Nov 01, 2012 4:03 am Post subject: |
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| LanDroid wrote: | ...
WCG / GO Fight against Malaria
Ummm haven't figgered out the stats on this sub-project? But you can score badges!
Oh well, here are overall WCG stats:
126th place
54,851,565 total points
51.5K average daily points in last week
60,362 123rd place |
Some additional KWSN's WCG / GFAM starting stats (Last Updated: 31.10.2012 23:59:59 UTC):
Total WCG points: 12,290,969
Total Bbucks (aka Boinc Credits): 1,755,853
Total Run Time (y:d:h:m:s): 8:348:19:15:54
Result returned: 11,862
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branjo
Prince
Joined: 05 Jan 2006
Posts: 746
Location: Slovakia
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| Posted: Thu Nov 01, 2012 4:37 am Post subject: |
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My WCG / GFAM starting stats:
Total WCG points: 226,457
Total Bbucks: 32,351
Total Run Time (y:d:h:m:s): 0:044:23:32:11 (Brown badge)
Result returned: 208
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Thu Nov 01, 2012 5:52 pm Post subject: |
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The FightMalaria project has small WUs that are fairly quick to process. I just started this morning and already have over 500 points in credit.
Ni
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Sir Papa Smurph
Cries like a little girl
Joined: 18 Jul 2006
Posts: 4430
Location: Michigan
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| Posted: Thu Nov 01, 2012 6:10 pm Post subject: |
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I only have 8 cores and I am running Poem & Prime Grid. Those projects reserve a core for each Gpu core and I have 6. It is unlikely I will be able to contribute much. I am thinking of getting some 8 cores but that will have to wait on finances....
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a.k.a. Licentious of Borg.........Resistance Really is Futile.......
and a Really Hoopy Frood who always knows where his Towel is...
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Concrete-mixing Moose
Prince
Joined: 30 Apr 2012
Posts: 567
Location: The Joyce Grenfell Home for the Distressed
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| Posted: Fri Nov 02, 2012 1:13 am Post subject: |
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| Killerrabbit wrote: | The FightMalaria project has small WUs that are fairly quick to process. I just started this morning and already have over 500 points in credit.
Ni |
There seems to be a bug in Fight Malaria's client that means it does n't get suspended when told to do so by the Boinc Manager. It will keep running even though the Boinc Manager shows a suspended status, and whatever else should be running shows as running but shows 0% progress, because the Fight Malaria client is still using the CPU. I had to use Task Manager to stop it.
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Sir Papa Smurph
Cries like a little girl
Joined: 18 Jul 2006
Posts: 4430
Location: Michigan
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| Posted: Fri Nov 02, 2012 4:45 am Post subject: |
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That might be why I had a Poem Wu run for almost 4 hours yesterday. they normally take ~55min
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a.k.a. Licentious of Borg.........Resistance Really is Futile.......
and a Really Hoopy Frood who always knows where his Towel is...
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Concrete-mixing Moose
Prince
Joined: 30 Apr 2012
Posts: 567
Location: The Joyce Grenfell Home for the Distressed
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| Posted: Fri Nov 02, 2012 7:47 am Post subject: |
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That's how I spotted it. It would n't let a POEM GPU WU get a core so it stood at 0% progress.
You have been warned!
Edit/Update from Kevin (a man with 3 hats -Project developer, Project tester & Project scientist) on this messageboard thread
| Quote: | Yep, it's a known bug. We were working on a fix but got side tracked by credit issues. We should have an update to correct this in the next two weeks.
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Fri Nov 02, 2012 3:44 pm Post subject: |
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| Concrete-mixing Moose wrote: | | Killerrabbit wrote: | The FightMalaria project has small WUs that are fairly quick to process. I just started this morning and already have over 500 points in credit.
Ni |
There seems to be a bug in Fight Malaria's client that means it does n't get suspended when told to do so by the Boinc Manager. It will keep running even though the Boinc Manager shows a suspended status, and whatever else should be running shows as running but shows 0% progress, because the Fight Malaria client is still using the CPU. I had to use Task Manager to stop it.
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I am not having that issue right now. Just going through WUs like butter. Over 2K already.
Ni
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Concrete-mixing Moose
Prince
Joined: 30 Apr 2012
Posts: 567
Location: The Joyce Grenfell Home for the Distressed
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| Posted: Sat Nov 03, 2012 7:35 am Post subject: |
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It seems like linux runs quicker then Windoze at Fight Malaria.
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sat Nov 03, 2012 9:51 am Post subject: |
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"We should have an update to correct this in the next two weeks. "
I was wondering why FightMalaria is so aggressive - guess I'll return to it in two weeks, moving on to the other two projects. Thanks for digging that up Sir Moose. |
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Killerrabbit
Major Oblivion
Joined: 23 May 2002
Posts: 4656
Location: in a rabbit hole near you!!
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| Posted: Sun Nov 04, 2012 12:40 am Post subject: |
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Plenty of bad mosquitoes to fight anyway.
Ni
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Blurf
Prince
Joined: 03 Jan 2011
Posts: 1090
Location: Upstate NY
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| Posted: Sun Nov 04, 2012 2:30 pm Post subject: |
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Wish I could do the GPU's for HCC and Malaria CPU's on the same project.
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LanDroid
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Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sat Nov 10, 2012 8:35 am Post subject: |
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| Quote: | Setback for first malaria vaccine in African trial
The world's first potential malaria vaccine proved only 30 percent effective in African babies in a crucial trial, calling into question whether it can be a useful weapon in the fight against the deadly disease. The surprisingly poor result for the vaccine, which GlaxoSmithKline has been developing for three decades, leaves several years of work ahead before a protective malaria shot could be ready for countries that desperately need one.
http://www.reuters.com/article/2012/11/09/us-malaria-vaccine-gsk-idUSBRE8A80I120121109 |
Need more shrubbing power to keep this effort going!
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PhastPhred
Prince
Joined: 22 Mar 2006
Posts: 6017
Location: Northwest AR (USA)
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| Posted: Sat Nov 10, 2012 9:50 am Post subject: |
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One solution to Malaria in Africa is the possibility of moving the entire population here to the U.S. - Abracadabra! - Africa no longer has ANY cases of Malaria!
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branjo
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Joined: 05 Jan 2006
Posts: 746
Location: Slovakia
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| Posted: Sat Nov 10, 2012 11:27 am Post subject: |
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| LanDroid wrote: | | Quote: | Setback for first malaria vaccine in African trial
The world's first potential malaria vaccine proved only 30 percent effective in African babies in a crucial trial, calling into question whether it can be a useful weapon in the fight against the deadly disease. The surprisingly poor result for the vaccine, which GlaxoSmithKline has been developing for three decades, leaves several years of work ahead before a protective malaria shot could be ready for countries that desperately need one.
http://www.reuters.com/article/2012/11/09/us-malaria-vaccine-gsk-idUSBRE8A80I120121109 |
Need more shrubbing power to keep this effort going!
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The sound of reason. Fully agree with you LanDroid.
Cheers and
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sun Nov 11, 2012 8:53 am Post subject: |
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Fight Malaria
KWSN have moved up 2 to 10th place! Stomp opportunties are good, we should pass another 3 or 4 teams. Just cracked 1 million points. Production is up to 38K daily average over the past week, which puts us in 4th place for shrubbation rates.
Any update on the aggressive behavior of these WU's, are they behaving better on the Boinc playground?
Malaria Control
Production is up slightly to 24K daily average. Need help on this one, we can pass Norway.
WCG/GO Fight Malaria
Production is up from 55K to 85K daily. We've actually fallen several spots.
WCG Badge News
I just got my silver badge for 45 days of skeeter-swatting and man does my arm hurt! 
Anyone else?
Milestones:
The Free-DC stats site has been under repair for several days, so no details at this time... |
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sun Nov 11, 2012 9:16 am Post subject: |
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I hope Knights spend some time checking out the science behind these projects, it's varied and intersting. I'll post a bit now & then...
Malaria Control Science
As the name suggests, this project focuses on how to reduce the spread of malaria, not an actual cure. One research project answered a detailed question about the optimal strategy for distributing a malaria vaccine. Here's another research area:
| Quote: | ...we'd like to tell you about another problem we looked at with your model runs - an analysis to see which factors were most important to determine the effective lifetime of long-lasting insecticide treated nets.
Long-lasting insecticide treated nets work: we know they reduce malaria transmission by protecting people from infectious bites. But even more important from a malaria control perspective, the nets keep the mosquitos from getting malaria from infected humans. In short, how long can we expect the epidemiological effect of these long-lasting nets to last?
We ran simulation models to explore the influence of pre-intervention transmission level, initial coverage, net attrition, and both physical and chemical net decay. The effective lifetime was most sensitive to the pre-intervention transmission level, with a lifetime of almost 10 years at an entomological inoculation rate of two infectious bites per adult per year, but of little more than 2 years at 256 two infectious bites per adult per year. The LLIN attrition rate and the insecticide decay rate were the next most important parameters. The lifetime was surprisingly insensitive to physical decay parameters, but this could change as physical integrity gains importance with the emergence and spread of insecticide resistance.
The strong dependency of the effective lifetime on the pre-intervention transmission level indicated that the required distribution frequency may vary more with the local entomological situation than with quality of the net or the characteristics of the distribution system. This highlights the need for malaria monitoring both before and during intervention programmes, particularly since there are likely to be strong variations between years and over short distances.
Abstract:
http://www.malariajournal.com/content/11/1/20/abstract
Full report:
http://www.malariajournal.com/content/pdf/1475-2875-11-20.pdf
http://www.malariacontrol.net/forum_thread.php?id=1264&nowrap=true#19059 |
Last edited by LanDroid on Sun Nov 11, 2012 9:26 am; edited 1 time in total |
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LanDroid
Prince
Joined: 11 Jun 2002
Posts: 4476
Location: Cincinnati, OH U.S.
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| Posted: Sun Nov 11, 2012 9:26 am Post subject: |
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Fight Malaria Science
| Quote: | Context: Malaria kills a child every 45 seconds. The disease is most prevalent in poorer countries, where it infects 216 million people and kills 650,000 each year, mostly African children under 5 years old [WHO]. And Plasmodium falciparum continues to evolve resistance to available medication. We therefore urgently need to discover new drugs to replace existing drugs. Importantly, these new drugs need to target NEW proteins in the parasite. The FightMalaria@Home project is aimed at finding these new targets.
Resources: The Plasmodium falciparum genome has been sequenced, the proteome has been mapped, and protein expression has been confirmed at various stages in this apicoplexan's life cycle. Numerous crystal structures of target proteins are also available, and the remainder have been modelled using available structural templates. Excitingly, large research organisations (GSK, Novartis) have already tested millions of compounds and found nearly 19,000 hits that show promising activity against Plasmodium falciparum [MMV]. But they don't know which target protein is inhibited by these compounds. Drug discovery and development will be significantly enhanced by knowing the target protein for each of these hits.
Problem: We plan to dock each of the 18,924 hits into structures of each of the 5,363 proteins in the malaria parasite. The computational power needed is enormous.
http://www.fight-malaria.org/ |
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